Water → HCID 10310661, compound

HRID 967317Notes

Reaction equation

HRID 967317 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][C:5]([CH2:8]Cl)=[CH:4][CH:3]=1.[CH3:10][O:11][C:12]1[CH:13]=[C:14]([C:20]2[C@@H:29]3[C@@H:24]([CH2:25][CH:26]=[CH:27][CH2:28]3)[C:23](=[O:30])[N:22]([CH:31]3[CH2:36][CH2:35][N:34](C4C=CC([N+]([O-])=O)=CC=4)[CH2:33][CH2:32]3)[N:21]=2)[CH:15]=[CH:16][C:17]=1[O:18][CH3:19].O>C(OCC)C>[CH3:10][O:11][C:12]1[CH:13]=[C:14]([C:20]2[C@@H:29]3[C@@H:24]([CH2:25][CH:26]=[CH:27][CH2:28]3)[C:23](=[O:30])[N:22]([CH:31]3[CH2:36][CH2:35][N:34]([CH2:8][C:5]4[CH:6]=[CH:7][N:2]=[CH:3][CH:4]=4)[CH2:33][CH2:32]3)[N:21]=2)[CH:15]=[CH:16][C:17]=1[O:18][CH3:19]

Participants

5

Reactant 3

HCID 962WaterHCID 745704-(Chloromethyl)pyridinium chlorideHCID 10128150HCID 10128150, compound

Product 1

HCID 10310661HCID 10310661, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Prepared from starting compound A1 and 4-picolylchloride hydrochloride as described for compound 11. After the addition of 100 ml of water, 20 ml of diethyl ether is added and the resulting mixture stirred for 30 min. The precipitate is filtered off and dried. M. p. 196-197° C.

Workup

  1. customPrepared
  2. additionis added
  3. filtrationThe precipitate is filtered off
  4. customdried

Sources & evidence

ORD record
ord-5a8d9932124e4be29b88620df23618f6
Source dataset
uspto-grants-2005_10
Patent number
US06953853B2

Reaction notes

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