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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 96748Generated: October 26, 2026

1-(4-fluorophenyl)-N-methylmethanamine → 2-{6-[(4-Difluoromethoxy-benzyl)-methyl-amino]-pyrazin-2-yl}-4-methyl-thiazole-5-carboxylic acid 4-fluoro-benzylamide

https://huagongshe.com/reaction/96748

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-fluorophenyl)-N-methylmethanamineHCID 736860—
Reactant{[4-(Difluoromethoxy)phenyl]methyl}(methyl)amineHCID 3857668—
Reactant2-(6-Iodo-pyrazin-2-yl)-4-methyl-thiazole-5-carboxylic acid 4-fluoro benzylamideHCID 86645558—
Product2-{6-[(4-Difluoromethoxy-benzyl)-methyl-amino]-pyrazin-2-yl}-4-methyl-thiazole-5-carboxylic acid 4-fluoro-benzylamideHCID 24955765—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-4e298bb6207b4791bf4f6610418bcd6d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)