Pyridine → HCID 178487535, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of the product from Step B (1 g, 6.1 mmol) in pyridine (0.5 mL, 6.1 mmol) was added phosphorous oxychloride (0.9 mL, 9.2 mmol) and the mixture heated at 130–140° C. for 5 h. The reaction mixture was cooled to 70° C. and poured onto ice (100 g). After standing for 24 h, the solid was collected and dried to give a cream-colored solid (0.42 g): ES/LCMS m/z 181 (M−H)+.

Provenance & Evidence