HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-isocyanatobenzoate → 3-{[3-(Adamantan-1-yloxymethyl)-1-cyclohexyl-5-methoxy-1H-pyrazole-4-carbonyl]-amino}-benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-isocyanatobenzoate | HCID 589806 | — |
| Reactant | 3-(adamantan-1-yloxymethyl)-4-bromo-1-cyclohexyl-5-methoxy-1H-pyrazole | HCID 22291997 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 3-{[3-(Adamantan-1-yloxymethyl)-1-cyclohexyl-5-methoxy-1H-pyrazole-4-carbonyl]-amino}-benzoic acid ethyl ester | HCID 69797945 | — |
Reaction Steps
The compound was prepared by treating 3-(adamantan-1-yloxymethyl)-4-bromo-1-cyclohexyl-5-methoxy-1H-pyrazole with n-butyl lithium and 3-ethoxycarbonylphenyl isocyanate as outlined in Reaction Scheme 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06956053B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-80f314bec98f4d5ab6cec140260bf8b9 |
| Source note | uspto-grants-2005_10 |