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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 967804Generated: October 30, 2026

Methyl iodide → 5-(Adamantan-1-yloxymethyl)-4bromo-2-cyclohexyl-1-methyl-1,2-dihydropyrazol-3-one

https://huagongshe.com/reaction/967804

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium hydrideHCID 24758—
Reactant5-(Adamantan-1-yloxymethyl)-4-bromo-2-cyclohexyl-1,2-dihydro-pyrazol-3-oneHCID 22291983—
Product5-(Adamantan-1-yloxymethyl)-4bromo-2-cyclohexyl-1-methyl-1,2-dihydropyrazol-3-oneHCID 22291990—

Reaction Steps

The compound was prepared by treating 5-(adamantan-1-yloxymethyl)-4-bromo-2-cyclohexyl-1,2-dihydro-pyrazol-3-one with sodium hydride and methyl iodide as outlined in Reaction Scheme 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06956053B2
Source datasetuspto-grants-2005_10
ORD IDord-036411df8fe84b22a2d9678333b2e192
Source noteuspto-grants-2005_10