4,5-Diphenylimidazole → HCID 86590299, compound

HRID 967808Notes

Reaction equation

HRID 967808 reaction equation
[C:1]1([C:7]2[N:8]=[CH:9][NH:10][C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:18][C:19]1[CH:24]=[CH:23][C:22]([S:25]([NH:28][C:29]([O:31][CH2:32][CH2:33][C:34]2[CH:39]=[CH:38][C:37](B(O)O)=[CH:36][CH:35]=2)=[O:30])(=[O:27])=[O:26])=[CH:21][CH:20]=1>>[CH3:18][C:19]1[CH:24]=[CH:23][C:22]([S:25]([NH:28][C:29](=[O:30])[O:31][CH2:32][CH2:33][C:34]2[CH:35]=[CH:36][C:37]([N:8]3[C:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)=[C:11]([C:12]4[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=4)[N:10]=[CH:9]3)=[CH:38][CH:39]=2)(=[O:26])=[O:27])=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 695884,5-DiphenylimidazoleHCID 218765304-{2-[({[(4-Methylphenyl)sulfonyl]amino]carbonyl)oxy]ethyl}phenylboronic acid

Product 1

HCID 86590299HCID 86590299, compound

Procedure

The title compound was prepared according to the procedure described in step 3 of Example 1 from 4,5-diphenylimidazole and 4-{2-[({[(4-Methylphenyl)sulfonyl]amino}carbonyl)oxy]ethyl}phenylboronic acid: MS (ESI) m/z 538 [M+H]+, 536 [M−H]−, 1H-NMR (CDCl3) δ 2.43 (3H, s), 2.84 (2H, t, J=6.6 Hz), 4.22-4.28 (2H, m), 6.86-6.95 (2H, m), 7.03-7.08 (4H, m), 7.21-7.52 (10H, m), 7.73 (1H, s), 7.85-7.90 (2H, m).

Sources & evidence

ORD record
ord-e0b0c43c1f0247ffa8008b1b1ba2e614
Source dataset
uspto-grants-2005_10
Patent number
US06956050B2

Reaction notes

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