Benzenesulfonyl isocyanate, 2-chloro- → 2-chloro-N-[({2-[4-(2-ethyl-4-phenyl-1h-imidazol-1-yl)phenyl]ethyl}amino) carbonyl]benzenesulfonamide

関与物質

反応手順

The title compound was prepared according to the procedure described in step 1 of Example 7 from 2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylamine and 2-chlorobenzensulfonyl isocyanate. MS (ESI) m/z 509 [M+H]+, 507 [M−H]−, 1H-NMR (DMSO-d6) δ 1.17 (3H, t, J=7.3 Hz), 2.63 (2H, q, J=7.5 Hz), 2.73 (2H, t, J=7.1 Hz), 3.19-3.27 (2H, m), 6.45 (1H, br), 7.20 (1H, t, J=7.3 Hz), 7.30-7.41 (6H, m), 7.49-7.55 (1H, m), 7.61 (1H, br), 7.73 (1H, s), 7.80 (2H, d, J=8.4 Hz), 8.03 (1H, dd, J=7.31 Hz).

情報源と証拠