4-Chlorobenzenesulfonamide → 4-chloro-N-[({2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethyl}amino)carbonyl]benzenesulfonamide

関与物質

反応手順

The title compound was prepared according to the procedure described in step 2 of Example 18 from 2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylcarbamate and 4-chlorobenzenesulfonamide. MS (ESI) m/z 509 [M+H]+, 507 [M−H]−, 1H-NMR (DMSO-d6) δ 1.14 (3H, t, J=7.5 Hz), 2.62 (2H, q, J=7.5 Hz), 2.72 (2H, t, J=7.1 Hz), 3.18-3.30 (2H, m), 6.60 (1H, t, J=5.7 Hz), 7.19 (1H, tt, J=7.3, 1.3 Hz), 7.28-7.38 (6H, m), 7.64-7.70 (2H, m), 7.76-7.80 (2H, m), 7.88 (2H, dt, J=11.2, 2.6 Hz).

情報源と証拠