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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 967826Generated: October 25, 2026

4-Fluorobenzenesulfonamide → 4-fluoro-N-[({2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethyl}amino)carbonyl]benzenesulfonamide

https://huagongshe.com/reaction/967826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzenesulfonamideHCID 120231—
Reactant2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylcarbamateHCID 22291350—
Product4-fluoro-N-[({2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethyl}amino)carbonyl]benzenesulfonamideHCID 10311206—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 18 from 2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylcarbamate and 4-fluorobenzenesulfonamide. MS (ESI) m/z 493 [M+H]+, 491 [M−H]−, 1H-NMR (CDCl3) δ 1.23 (3H, t, J=7.5 Hz), 2.68 (2H, q, J=7.7 Hz), 2.87 (2H, t, J=7.0 Hz), 3.42-3.60 (2H, m), 6.46 (1H, br), 7.16-7.28 (7H, m), 7.37 (2H, t, J=7.3 Hz), 7.76 2H, d, J=7.1 Hz), 7.85-7.91 (2H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06956050B2
Source datasetuspto-grants-2005_10
ORD IDord-b3e6c7682256429aae52b730d45917fd
Source noteuspto-grants-2005_10