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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 967828Generated: October 25, 2026

4-Methoxybenzenesulfonamide → 4-methoxy-N-[({2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethyl}amino)carbonyl]benzenesulfonamide

https://huagongshe.com/reaction/967828

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzenesulfonamideHCID 70789—
Reactant2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylcarbamateHCID 22291350—
Product4-methoxy-N-[({2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethyl}amino)carbonyl]benzenesulfonamideHCID 22291353—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 18 from 2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylcarbamate and 4-methoxybenzenesulfonamide. MS (ESI) m/z 505 [M+H]+, 503 [M−H]−, 1H-NMR (CDCl3) δ 1.25 (3H, t, J=7.5 Hz), 2.72 (2H, q, J=7.5 Hz), 2.91 (2H, t, J=6.8 Hz), 3.40-3.55 (2H, m), 6.64 (1H, br), 6.96 (2H, d, J=9.0 Hz), 7.20-7.30 (5H, m), 7.38 (2H, t, J=7.3 Hz), 7.74 (2H, d, J=9.0 Hz), 7.79 (2H, d, J=8.4 Hz).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06956050B2
Source datasetuspto-grants-2005_10
ORD IDord-8469e0c746d140fd96f5c4308af0aef9
Source noteuspto-grants-2005_10