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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 967829Generated: October 25, 2026

2-Fluorobenzenesulfonamide → 2-fluoro-N-[({2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethyl}amino)carbonyl]benzenesulfonamide

https://huagongshe.com/reaction/967829

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzenesulfonamideHCID 193663—
Reactant2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylcarbamateHCID 22291350—
Product2-fluoro-N-[({2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethyl}amino)carbonyl]benzenesulfonamideHCID 22291357—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 18 from 2-[4-(2-ethyl-4-phenyl-1H-imidazol-1-yl)phenyl]ethylcarbamate and 2-fluorobenzenesulfonamide. MS (ESI) n/z 500 [M+H]+, 498 [M−H]−, 1H-NMR (CDCl3) δ 1.23 (3H, t, J=6.0 Hz), 2.71 (2H, q, J=6.0 Hz), 2.84 (2H, t, J=6.0 Hz), 3.44-3.52 (2H, m), 6.58 (1H, br), 7.18-7.30 (7H, m), 7.37 (2H, t, J=9.0 Hz), 7.59-7.65 (1H, m), 7.78 (2H, d, J=6.0 Hz), 7.84-7.90 (2H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06956050B2
Source datasetuspto-grants-2005_10
ORD IDord-777cb68dc020429abe101e8127d11d44
Source noteuspto-grants-2005_10