HCID 21875993, compound → HCID 21876484, compound

Participants

Reaction Steps

To a stirred solution of 2-[4-(2-nitroanilino)phenyl]ethanol (2.0 g, 7.6 mmol) in methanol (15 mL) was added 10% Pd—C (160 mg). The mixture was stirred at room temperature for 6 h under hydrogen atmosphere. The palladium catalyst was removed by filtration and washed with ethanol (100 mL). The filtrate was concentrated under reduced pressure to afford 1.6 g (92%) of the title compound as pale yellow solids: 1H-NMR (CDCl3)δ2.79 (2H, t, J=6.6 Hz), 3.75 (2H, br), 3.80 (2H, t, J=6.6 Hz), 5.14 (1H, s), 6.82-6.66 (4H, m), 7.15-6.96 (4H, m).

Provenance & Evidence