Hydrochloric Acid → HCID 21912326, compound

Participants

Reaction Steps

The title compound was prepared by hydrogenation of (1-ethyl-propyl)-[2-methyl-5-nitro-6-(2,4,6-trimethyl-phenoxy)-pyrimidin-4-yl]-amine by the method analogous to that described in Example 93. 1H NMR (CDCl3) δ 6.88 (s, 2H), 4.52 (d, 1H), 4.10 (m, 1H), 2.94 (brs, 2H), 2.30 (s, 3H), 2.23 (s, 3H), 2.09 (s, 6H), 1.4-1.8 (m, 4H), 0.95 (t, 6H) ppm. The corresponding HCl salt, mp 248-250° C. 1H NMR (CD3OD) δ 6.91 (s, 2H), 4.00 (m, 1H), 2.39 (s, 3H), 2.28 (s, 3H), 2.07 (s, 6H), 1.6-1.8 (m, 4H), 1.00 (t, 6H) ppm.

Provenance & Evidence