Triacetoxyperiodinane → 2-(4-Chloro-2,6-dimethyl-phenoxy)-4-(1-ethyl-2-oxo-propylamino)-6-methyl-nicotinic acid methyl ester

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The title compound was prepared by Dess-Martin oxidation of 2-(4-chloro-2,6-dimethyl-phenoxy)-4-(1-ethyl-2-hydroxy-propylamino)-6-methyl-nicotinic acid methyl ester. A white solid was obtained after silica gel column chromatography. 1H NMR(CDCl3) d 8.6(d, 1H), 7.01(s, 2H), 5.899s, 1H), 3.9-4.0(m, 1H), 3.90(s, 3H), 2.17(s, 3H), 2.07(s, 3H), 2.05(s, 3H), 1.859m, 1H), 1,93(m, 1H), 1.00(t, 3H) ppm.

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