2-Chloroisonicotinic acid → HCID 22291543, compound

HRID 968114Notes

Reaction equation

HRID 968114 reaction equation
[NH2:1][C:2]1[CH:24]=[CH:23][C:5]2[CH2:6][CH2:7][C:8]3[C:9]([C:20]([NH2:22])=[O:21])=[N:10][N:11]([C:13]4[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=4)[C:12]=3[C:4]=2[CH:3]=1.[Cl:25][C:26]1[CH:27]=[C:28]([CH:32]=[CH:33][N:34]=1)[C:29](O)=[O:30]>>[Cl:25][C:26]1[CH:27]=[C:28]([CH:32]=[CH:33][N:34]=1)[C:29]([NH:1][C:2]1[CH:24]=[CH:23][C:5]2[CH2:6][CH2:7][C:8]3[C:9]([C:20]([NH2:22])=[O:21])=[N:10][N:11]([C:13]4[CH:14]=[CH:15][C:16]([F:19])=[CH:17][CH:18]=4)[C:12]=3[C:4]=2[CH:3]=1)=[O:30]

Participants

3

Reactant 2

HCID 2369852-Chloroisonicotinic acidHCID 22291910HCID 22291910, compound

Product 1

HCID 22291543HCID 22291543, compound

Procedure

This material was prepared from Example 244 (8-amino-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide) and 2-chloroisonicotinic acid by the method described for Example 246 step 3.

Sources & evidence

ORD record
ord-eead182ffe8b49cfb21ce59e47c8dc21
Source dataset
uspto-grants-2005_10
Patent number
US06956052B2

Reaction notes

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