Sodium 4-methylbenzenesulfonate → 4-Methylphenylbenzylpiperidinium tosylate

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Reaction Steps

An aqueous solution prepared by dissolving 4-methylphenylbenzylpiperidinium bromide (13.85 g, 0.04 mmol) and sodium p-toluenesulfonate (9.32 g, 0.048 mmol) in 50 ml of deionized water was extracted with 50 ml of chloroform twice by using a separating funnel. The resulting chloroform phases were combined and the combined solution was washed with 50 ml of deionized water, followed by filtration and drying to obtain 4-methylphenylbenzylpiperidinium tosylate (16.1 g, yield: 92%).

Provenance & Evidence