Phosphorus oxychloride → HCID 22288471, compound

Participants

Reaction Steps

The product from step (b), (8.7 g), was suspended in phosphorus oxychloride (88 ml) and dimethylaniline (8.8 ml). The mixture was heated under reflux for 2 hrs then evaporated. The residue was stirred in hot water, cooled and the pH adjusted with sodium hydroxide solution to pH5. The solid was collected, washed with water and dried. Chromatography (SiO2, methanol/dichloromethane as eluant) gave the sub-title compound (4.3 g)

Provenance & Evidence