HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Tert-Butylaniline →
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Tert-Butylaniline | HCID 69861 | — |
| Reactant | 4-Chloro-7-[3-(trifluoromethyl)-2-pyridinyl]quinazoline | HCID 22030384 | — |
| Solvent | Isopropanol | HCID 3776 | — |
Reaction Steps
Stir 4-chloro-7-(3-trifluoromethyl-pyridin-2-yl)-quinazoline (0.16 mmol) and 4-tert-butyl-aniline (0.32 mmol) in IPA (4 mL) at 80° C. for 6 hours. Cool the mixture and collect the precipitate to obtain (4-tert-Butyl-phenyl)-[7-(3-trifluoromethyl-pyridin-2-yl)-quinazolin-4-yl] hydrochloride. Mass spec. 422.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07304059B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-15f4cd1d245940d5b3c430f4b90729b2 |
| Source note | uspto-grants-2007_12 |