Acetate → HCID 178430523, compound

HRID 968775Notes

Reaction equation

HRID 968775 reaction equation
CC([O-])=O.N1CCN=C1[NH:10][C:11]1[CH:12]=[C:13]([C:21]#[N:22])[C:14]2[N:18]=[CH:17][NH:16][C:15]=2[C:19]=1[CH3:20].S(=O)(=O)(O)O>>[NH2:10][C:11]1[CH:12]=[C:13]([C:21]#[N:22])[C:14]2[N:18]=[CH:17][NH:16][C:15]=2[C:19]=1[CH3:20]

Participants

4

Reactant 3

HCID 175AcetateHCID 1118Sulfuric AcidHCID 178430142HCID 178430142, compound

Product 1

HCID 178430523HCID 178430523, compound

Procedure

A comparison of the solubility of the presently claimed anhydrous monoacetate salt of 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile and that of previously disclosed sulfuric acid salt and free base form is presented as Example 18.

Sources & evidence

ORD record
ord-0034b103a59644dea6ea4b4c5aeba274
Source dataset
uspto-grants-2007_12
Patent number
US07304084B2

Reaction notes

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