Dimethylformamide dimethyl acetal → N'-(6-Cyano-3-methyl-2,4-dinitro-phenyl)-N,N-dimethyl-methanimidamide

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Reaction Steps

To a suspension of 2-amino-4-methyl-3,5-dinitrobenzonitrile (5) (3.129 g, 14.1 mmol) in anhydrous toluene is added N,N-dimethylformamide dimethyl acetal (4 mL). The resultant mixture is heated to about 100° C. for about 2.5 hours. The mixture is cooled to ambient temperature and the solvent is removed using a rotary evaporator. The residue is dried to provide crude N′-(6-Cyano-3-methyl-2,4-dinitro-phenyl)-N,N-dimethyl-methanimidamide (8) (3.85 g, 99% Yield) as a red solid.

Provenance & Evidence