HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(cyclohexylamino)-3-nitrobenzoate → Methyl 3-amino-4-(cyclohexylamino)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(cyclohexylamino)-3-nitrobenzoate | HCID 2972846 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-amino-4-(cyclohexylamino)benzoate | HCID 4083987 | 99% |
Reaction Steps
Compound 50 (10.57 g, 37.9 mol) was hydrogenated in MeOH (130 mL) over 5% Pd/C (150 mg) under H2 for 30 minutes. The reaction was filtered through Celite and the solution was evaporated to give a brown solid (9.4 g, 99%). MS (ESI) 249.17 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07304085B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-24eb5018382e49dd92d20538c8e79af9 |
| Source note | uspto-grants-2007_12 |