Benzyl Bromide → HCID 178420434, compound

Participants

Reaction Steps

To a stirring solution of the compound of Example 1 (c) (23 mg, 0.12 mmol) in 1.2 mL of DMF was added K2CO3 (17 mg, 0.12 mmol), followed by benzyl bromide (20 mg, 0.12 mmol). The mixture was stirred overnight, filtered, and purified by preparative HPLC to afford the title compound as a white solid (30 mg, 70%). 1H-NMR (400 MHz, d6-DMSO) δ9.30 (broad singlet, 1H), 7.47 (d, 2H, J=8.1 Hz), 7.39 (d, 2H, J=7.3 Hz), 7.31 (t, 2H, J=7.3 Hz), 7.23 (quartet, 3H, J=7.3 Hz), 6.82 (t, 1H, J=7.3 Hz), and 4.3 (s, 2H).

Provenance & Evidence