HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malic Acid → HCID 178507297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malic Acid | HCID 525 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2,6-Diaminopyridine | HCID 8861 | — |
| Product | HCID 178507297 | HCID 178507297 | — |
Reaction Steps
In step 1 of the method, commercially available 2,6-diaminopyridine (e.g., Aldrich, Milwaukee, Wis.) is reacted with malic acid in sulfuric acid to provide 2-amino-7-hydroxy-1,8-naphthyridine sulfuric acid salt. It is noted that 2-amino-7-hydroxy-1,8-naphthyridine free base is described in S. Carboni et al., Gazz. Chim. Ital., 95, 1498 (1965).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07304158B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-aead605fb5214611a6d922e67e171bc0 |
| Source note | uspto-grants-2007_12 |