2,6-Diacetylpyridine → HCID 76843609, compound

HRID 968893Notes

Reaction equation

HRID 968893 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10](=O)[CH3:11])[N:5]=1)(=O)[CH3:2].[NH2:13][N:14]1[CH:18]=[CH:17][CH:16]=[CH:15]1>C1(C)C=CC=CC=1>[N:14]1([N:13]=[C:1]([C:4]2[CH:9]=[CH:8][CH:7]=[C:6]([C:10](=[N:13][N:14]3[CH:18]=[CH:17][CH:16]=[CH:15]3)[CH3:11])[N:5]=2)[CH3:2])[CH:18]=[CH:17][CH:16]=[CH:15]1

Participants

4

Reactant 2

HCID 707902,6-DiacetylpyridineHCID 1365891-Aminopyrrole

Product 1

HCID 76843609HCID 76843609, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2,6-Diacetylpyridine (345 mg, 2.11 mmol) and 1-aminopyrrole (400 mg, 4.87 mmol) were dissolved in 50 ml of toluene. To this solution, molecular sieves (4 Å) were added. After standing for 2 days at room temperature, the mixture was filtered. The solvent was removed in vacuo. The residue was crystallised from ethanol. Yield 350 mg (57%) of diimine 11.

Workup

  1. additionTo this solution, molecular sieves (4 Å) were added
  2. filtrationthe mixture was filtered
  3. customThe solvent was removed in vacuo
  4. customThe residue was crystallised from ethanol

Sources & evidence

ORD record
ord-cc4731125b194782b917cd73b9059325
Source dataset
uspto-grants-2007_12
Patent number
US07304159B2

Reaction notes

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