4-Hydroxybenzoic Acid → 4-Hydroxybenzoic Acid
Reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[C:11]1([OH:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[OH-].[K+:19]>>[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[O-:17][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[K+:19]Participants
5
Procedure
Parahydroxybenzoic acid has been used for manufacturing a wide variety of products including liquid crystalline polymers and preservatives for cosmetics and medicines. Generally, parahydroxybenzoic acid is prepared by a method in which phenol is reacted with potassium hydroxide to give potassium phenoxide, and the obtained potassium phenoxide is reacted with carbon dioxide under pressure to give potassium parahydroxybenzoate and then, parahydroxybenzoic acid is isolated by means of aciding out procedure, i.e. by adding a mineral acid to the salt.
Sources & evidence
- ORD record
- ord-f9220f0131f548a5bd5493b8c099c161
- Source dataset
- uspto-grants-2007_12
- Patent number
- US07304182B2
Reaction notes
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