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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 969Generated: October 28, 2026

1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 5-[3-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl) propylsulfamoyl]-2,3,4,5-tetrahydro-1-benzoxepine

https://huagongshe.com/reaction/969

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 1519998—
Reactant5-(3-Chloropropylsulfamoyl)-2,3,4,5-tetrahydro-1-benzoxepineHCID 19694258—
Product5-[3-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl) propylsulfamoyl]-2,3,4,5-tetrahydro-1-benzoxepineHCID 70102646—

Reaction Steps

The compound (10) synthesized in Reference Example 10 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723475
Source datasetuspto-grants-1998_03
ORD IDord-5a9645c8c72546f59db841e4d13fd844
Source noteuspto-grants-1998_03