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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 969278Generated: October 31, 2026

3-Hydroxy-4'-methoxy-2-nitrobenzanilide → 2-Amino-3-hydroxy-4'-methoxybenzanilide

https://huagongshe.com/reaction/969278

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-4'-methoxy-2-nitrobenzanilideHCID 18001131—
ReactantHCID 178418361HCID 178418361—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
Product2-Amino-3-hydroxy-4'-methoxybenzanilideHCID 1800110793.8%

Reaction Steps

3-Hydroxy-4′-methoxy-2-nitrobenzanilide (1.15 g) was suspended in 50 ml of methanol, 300 mg of 10% palladium-carbon powder were added and the mixture was stirred in a hydrogen atmosphere at room temperature for 1 hour. The reaction solution was filtered through Celite and washed with methanol and the filtrate was concentrated in vacuo to give 966 mg of 2-amino-3-hydroxy-4′-methoxybenzanilide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07307074B2
Source datasetuspto-grants-2007_12
ORD IDord-38292be6e8b14797a05eb7502b9427f2
Source noteuspto-grants-2007_12