HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → 6-bromo-8-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Amino-4-bromo-6-fluorophenol | HCID 2737637 | — |
| Product | 6-bromo-8-fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one | HCID 46856463 | 97.3% |
Reaction Steps
2-Amino-4-bromo-6-flourophenol (95MF2084) (0.078 g, 0.38 mmol), 2-chloroacetyl chloride (0.048 g, 0.42 mmol) and K2CO3 (0.11 g, 0.79 mmol) were mixed according to GP1 to give the title compound as a crude (95MF44) (0.091 g)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307075B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-ab242d78bb194a5e9a24a497779863a4 |
| Source note | uspto-grants-2007_12 |