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HRID969331

反应详情

EQUATION

反应方程式

HRID 969331 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[Cs+].[Cs+]
HCID10796

Cesium carbonate

CCs2O3

结构：ClCCCI
HCID81363

1-Chloro-3-iodopropane

C3H6ClI

结构：O=C1COc2cc([N+](=O)[O-])c(Cl)cc2N1
HCID3305696

6-Chloro-7-nitro-2H-1,4-benzoxazin-3(4H)-one

C8H5ClN2O4

PRODUCTS

生成物

1
结构：O=C1COc2cc([N+](=O)[O-])c(Cl)cc2N1CCCCl
HCID68910914

未命名化合物

收率 40.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCCC.CCOC(C)=O
溶剂HCID21899848

未命名化合物

PROCEDURE

实验过程

Crude 6-Chloro-7-nitro-4H-benzo[1,4]oxazin-3-one (81MF2253a) (2.60 g, 10.0 mmol), Cs2CO3 (4.88 g, 15.0 mmol) and 3-chloro-1-iodopropane (2.25 g, 11.0 mmol) were mixed according to GP6. CC (SiO2; Heptane/EtOAc 10:1-5) gave the title compound (81MF2253b) (1.23 g, 36%). 1H NMR (CDCl3) δ 7.66 (s, 1H), 7.20 (s, 1H), 4.70 (s, 2H), 4.12 (t, J=7.6 Hz, 2H), 3.67-3.59 (m, 2H), 2.21-2.13 (m, 2H); 13C NMR (CDCl3) δ 163.6, 143.5, 133.3, 133.2, 122.4, 117.2, 115.2, 67.4, 42.1, 39.6, 29.8.