HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 6-hydroxy-2-naphthoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 6-Hydroxy-2-naphthoic acid | HCID 85557 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | Methyl 6-hydroxy-2-naphthoate | HCID 390995 | 84% |
Reaction Steps
A solution of 15.7 g (83.4 mmol) of 6-hydroxy-2-naphthoic acid is refluxed for 8 hours in a mixture of 160 ml of methanol and 8 ml of concentrated sulfuric acid. After cooling, the product precipitates out. After filtration and washing with isopropyl ether, 14.1 g of methyl 6-hydroxynaphthalene-2-carboxylate are obtained in the form of a beige-colored solid in a yield of 84%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307078B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-254080d33fd046a49aa7764d1420b975 |
| Source note | uspto-grants-2007_12 |