Water → HCID 69135242, compound

Participants

Reaction Steps

A solution of 4.6 g (12.5 mmol) 7-hydroxy-2,3-dimethyl-6-(3-oxo-phenylpropyl)-3H-benzimidazole-5-carboxylic acid ethyl ester in ethanol (200 ml) was treated with 570 mg (15.0 mmol) sodium borohydride and the reaction was stirred at room temperature for 3 h. A saturated ammonium chloride solution was added and the reaction was poured into water (200 ml). The precipitate was filtered off and dried in vacuo at 40° C. to afford 4.4 g (95%) of the title compound as a white solid. m.p. 193°-195° C.

Provenance & Evidence