Acetic Acid → HCID 69135082, compound

Participants

Reaction Steps

A solution of 3.6 g (10.3 mmol) 7-benzyloxy-2-isopropyl-3-methyl-3H-benzimidazole-5-carboxylic acid dimethylamide and 900 μl acetic acid in 70 ml methanol was hydrogenated over 885 mg 10% Pd/C in autoclave (5 bar H2) at 50° C. for 15 h. The catalyst was filtered off and the filtrate was concentrated in vacuo to afford 3.2 g (100%) of the title compound as a grey wax.

Provenance & Evidence