{5-[2,5-Difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl)methanol → Ethyl[4-({5-[2,5-difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)-2-methylphenoxy]acetate

Participants

Role	Name	HCID	Charge
Reactant	{5-[2,5-Difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl)methanol	HCID 21986329	—
Reactant	Ethyl (4-hydroxy-2-methylphenoxy)acetate	HCID 21986458	—
Reactant	Ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate	HCID 21986477	—
Product	Ethyl[4-({5-[2,5-difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)-2-methylphenoxy]acetate	HCID 21986311	—

Reaction Steps

The title compound was prepared by a method analogous to that used for the preparation of ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate (example 1) using ethyl(4-hydroxy-2-methylphenoxy)acetate (intermediate 7) and {5-[2,5-difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol (intermediate 120).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07091237B2
Source dataset	uspto-grants-2006_08
ORD ID	ord-ab08d73f10fa4a0ea110a92bbee126a5
Source note	uspto-grants-2006_08