HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-Dimethoxy-2,5-cyclohexadien-1-one → HCID 10430033, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-Dimethoxy-2,5-cyclohexadien-1-one | HCID 394648 | — |
| Reactant | 5-Fluoro-1-(phenylsulfonyl)-1H-indole | HCID 11288858 | — |
| Product | HCID 10430033 | HCID 10430033 | 21% |
Reaction Steps
The title compound was prepared from 4,4-dimethoxy-cyclohexa-2,5-dienone and 1-benzenesulfonyl-5-fluoro-1H-indole, according to Method C, described above. Yield 21%; mp 166-167° C.; 1H NMR (CDCl3) δ 8.03-8.09 (m, 1H), 7.94 (d, J=8 Hz, 2H), 7.51-7.70 (m, 5H), 7.12-7.20 (m, 2H), 6.86 (s, 1H), 6.42 (d, J=10 Hz, 2H), 5.49 (s, 1H); 13C NMR (CDCl3) δ 185.1, 162.4, 158.5, 147.6, 143.0, 137.7, 134.8, 129.9, 129.8, 129.7, 128.2, 126.9, 116.9, 116.8, 114.8, 114.4, 113.6, 107.8, 107.4, 67.9; MS (AP+) m/z 384.04 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307099B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-350cf3f8071d422db67931128b32bd78 |
| Source note | uspto-grants-2007_12 |