HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 59017453, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59017473 | HCID 59017473 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59017453 | HCID 59017453 | — |
Reaction Steps
In a manner similar to that described in Example 127, to a solution of tert-butyl 4,4-dimethyl-7-{2-[1-(2-methylamino-pyrimidin-4-yl)-ethylamino]-benzoylamino}-3,4-dihydro-1H-isoquinoline-2-carboxylate (250 mg, 0.471 mmol) in CH2Cl2 (5 mL) was added TFA (3 mL) to give the final product. MS m/z: 431.3 (M+H). Calc'd. for C25H31N6O-431.55.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307088B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-1dbbd593a8384912b9f15ab1861a876a |
| Source note | uspto-grants-2007_12 |