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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 969704Generated: October 30, 2026

Trifluoroacetic acid → HCID 59017453, compound

https://huagongshe.com/reaction/969704

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59017473HCID 59017473—
SolventDichloromethaneHCID 6344—
ProductHCID 59017453HCID 59017453—

Reaction Steps

In a manner similar to that described in Example 127, to a solution of tert-butyl 4,4-dimethyl-7-{2-[1-(2-methylamino-pyrimidin-4-yl)-ethylamino]-benzoylamino}-3,4-dihydro-1H-isoquinoline-2-carboxylate (250 mg, 0.471 mmol) in CH2Cl2 (5 mL) was added TFA (3 mL) to give the final product. MS m/z: 431.3 (M+H). Calc'd. for C25H31N6O-431.55.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07307088B2
Source datasetuspto-grants-2007_12
ORD IDord-1dbbd593a8384912b9f15ab1861a876a
Source noteuspto-grants-2007_12