HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → Methyl 2-(4-methoxyphenyl)benzoxazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | Anthranilic acid, 3-hydroxy-, methyl ester | HCID 205248 | — |
| Product | Methyl 2-(4-methoxyphenyl)benzoxazole-4-carboxylate | HCID 14616764 | 18% |
Reaction Steps
Methyl 2-(4-methoxyphenyl)benzoxazole-4-carboxylate was prepared from methyl 3-hydroxyanthranilate and 4-methoxybenzoyl chloride as described in Step A of Example 1. The product was obtained as an off-white solid in 18% yield. δ 8.29 (m, 2H), 8.01 (dd, J=7.8, 1.0 Hz, 1H), 7.74 (dd, J=8.1, 1.0 Hz, 1H), 7.37 (t, J=7.9 Hz, 1H), 7.03 (m, 2H), 4.06 (s, 3H); 3.91 (s, 3H); MS (ESI) m/z 284 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307094B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-b36fabee3cdf4182a85ed0bec8ffa501 |
| Source note | uspto-grants-2007_12 |