HRID9699

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID16756990

Ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoate

C13H18O4

2 次

结构：OC(c1ccccc1)c1csc(-c2ccc(C(F)(F)F)cc2)c1

HCID21986317

未命名化合物

2 次

结构：CCOC(=O)COc1ccc(SCc2coc(-c3ccc(C(F)(F)F)cc3)c2)cc1C

HCID21986477

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C(C)(C)Oc1ccc(OC(c2ccccc2)c2csc(-c3ccc(C(F)(F)F)cc3)c2)cc1C

HCID21986485

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by a method analogous to that used for the preparation of ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate (example 1) using ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoate (intermediate 10) and phenyl{5-[4-(trifluoromethyl)phenyl]thien-3-yl}methanol (intermediate 127).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6f988cea8bdb463dbc69ed0a7151a8a4
来源数据集: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07091237B2
来源说明: uspto-grants-2006_08

反应 SMILES

C(OC(=O)COC1C=CC(SCC2C=C(C3C=CC(C(F)(F)F)=CC=3)OC=2)=CC=1C)C.[OH:32][C:33]1[CH:47]=[CH:46][C:36]([O:37][C:38]([CH3:45])([CH3:44])[C:39]([O:41][CH2:42][CH3:43])=[O:40])=[C:35]([CH3:48])[CH:34]=1.[C:49]1([CH:55]([C:57]2[CH:61]=[C:60]([C:62]3[CH:67]=[CH:66][C:65]([C:68]([F:71])([F:70])[F:69])=[CH:64][CH:63]=3)[S:59][CH:58]=2)O)[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=1>>[CH3:44][C:38]([O:37][C:36]1[CH:46]=[CH:47][C:33]([O:32][CH:55]([C:49]2[CH:54]=[CH:53][CH:52]=[CH:51][CH:50]=2)[C:57]2[CH:61]=[C:60]([C:62]3[CH:63]=[CH:64][C:65]([C:68]([F:69])([F:70])[F:71])=[CH:66][CH:67]=3)[S:59][CH:58]=2)=[CH:34][C:35]=1[CH3:48])([CH3:45])[C:39]([O:41][CH2:42][CH3:43])=[O:40]