HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R,S)-Boc-2-amino-tetradecanoic acid → 2-(t-Butoxycarbonylamino)dodecanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R,S)-Boc-2-amino-tetradecanoic acid | HCID 2756016 | — |
| Reactant | 2,3,4,6-Tetra-o-acetyl-n-{1-(r/s)-[(tert-butoxycarbonyl)-amino]dodecyl}-beta-d-glucopyranosylamide | HCID 131726726 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 2-(t-Butoxycarbonylamino)dodecanol | HCID 15673750 | 87% |
Reaction Steps
Procedure as for 44 (using 40 in place of 41). RF=0.50 hexane:ethyl acetate 4:1 (v/v); yield 87%; 1H NMR δ 3.65-3.48 (m, 3H, αCH, CH2), 1.43 (s, 9H, 3×Boc CH3), 1.24 (m, 18H, 9CH2), 0.86 (t, 3H, CH3); FAB MS C17H35NO3 (301.46) m/z (%) 302 [M+H]+ (15), 324 [M+Na]+ (5), 434 [M+Cs]+ (10), 202 [M−Boc+H]+ (95).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312194B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-1558021506d94a2e9e99ed3df0dda994 |
| Source note | uspto-grants-2007_12 |