Acetic Anhydride → HCID 131726728, compound

Participants

Reaction Steps

tert-Butyl 1-{[3,4,6-tri-O-acetyl-2-deoxy-2-(2,2,2-trichloro-ethoxycarbonyl-amino)-β-D-glucopyranosyloxy]methyl}-(R/S)-undecyl-carbamate 50(27.0 mg, 0.0353 mmol) was dissolved in acetic anhydride (1 ml) into which activated zinc powder (4.6 mg, 0.0706 mmol) had been added. The reaction was stirred for 6 hours, after which it was filtered and evaporated (and co-evaporated with benzene and toluene). The residue was purified by column chromatography to give 51 (11 mg, 49%).

Provenance & Evidence