Triethylamine → 2,3,4,6-Tetra-o-acetyl-n-[({2-(r/s)-[(tert-butoxycarbonyl)amino]-dodecyl}amino)-carbonothioyl]-beta-d-glucopyranosylamine

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Reaction Steps

2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate 37 (25.0 mg, 0.0617 mmol), tert-butyl N-[1-(R/S)-(aminomethyl)-undecyl]carbamate (27.8 mg, 0.0927 mmol) and triethylamine (12.5 mg, 0.0124 mmol) were dissolved in abs. CH2Cl2 (5 ml) and stirred at room temperature for 1 hour. Following evaporation, the residue was purified by column chromatography to give 65 (42.0 mg, 94%)

Provenance & Evidence