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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 970320Generated: October 29, 2026

Methyl 2-amino-2-methylpropanoate → N-[(9,10-Dihydro-9-oxo-3-acridinyl)carbonyl]-2-methyl-alanine, methyl ester

https://huagongshe.com/reaction/970320

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-2-methylpropanoateHCID 4186341—
Reactant9-oxo-10H-acridine-3-carboxylic AcidHCID 11379438—
ProductN-[(9,10-Dihydro-9-oxo-3-acridinyl)carbonyl]-2-methyl-alanine, methyl esterHCID 131726731—

Reaction Steps

Example 128 was prepared from compound 1C by a route analogous to that used for the preparation of Example 1, replacing the amine in Step E with 2-Amino-2-methyl-propionic acid methyl ester. HPLC retention time=2.453 min./condition A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07312209B2
Source datasetuspto-grants-2007_12
ORD IDord-e6f41b9842b54298b51640f40bb57706
Source noteuspto-grants-2007_12