HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 9,10-Dihydro-7-methyl-9-oxo-3-acridinecarboxylic Acid, Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 9,10-Dihydro-7-methyl-9-oxo-3-acridinecarboxylic Acid | HCID 68563594 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 9,10-Dihydro-7-methyl-9-oxo-3-acridinecarboxylic Acid, Methyl Ester | HCID 86591421 | — |
Reaction Steps
A mixture of compound 138B (50 mg), MeOH (12 mL), Conc. H2SO4 (2 drops), and DMF (2 drops) was heated to reflux over 18 h. LC/MS indicated the reaction was complete. The reaction mixture was concentrated in vacuo to give a brown oil (47.5 mg). HPLC retention time: 3.05 min., condition: A. M+: 268.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312209B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-715694cf05ec42d8bb8b3d6821343aac |
| Source note | uspto-grants-2007_12 |