2-Chloro-6-methylpyridine-3-carbonitrile → HCID 18362992, compound
Reaction equation
Cl[C:2]1[N:9]=[C:8]([CH3:10])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH:11](C1C=CC(C#N)=CN=1)=[CH2:12]>>[CH3:10][C:8]1[CH:7]=[CH:6][C:3]([C:4]#[N:5])=[C:2]([CH:11]=[CH2:12])[N:9]=1Participants
3
Procedure
Compound 386A was prepared from 2-chloro-6-methyl-nicotinonitrile by a route analogous to that used for the preparation of compound 384A. HPLC retention time=1.81 min. (Condition A), M+=145.
Sources & evidence
- ORD record
- ord-28694f7b4619487ea1c92d62670dd8a9
- Source dataset
- uspto-grants-2007_12
- Patent number
- US07312209B2
Reaction notes
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