HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-7-nitro-1,2,3,4-tetrahydroquinoline → 1-Methyl-1,2,3,4-tetrahydroquinolin-7-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-7-nitro-1,2,3,4-tetrahydroquinoline | HCID 11480955 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-Methyl-1,2,3,4-tetrahydroquinolin-7-amine | HCID 11217421 | — |
Reaction Steps
A mixture of the 1-methyl-7-nitro-1,2,3,4-tetrahydroquinoline (4.0 g, 20.81 mMol), Pd/C (2 g) in methanol (100 mL) was hydrogenated at 10 PSI for 2 hours. The catalyst was filtered off, and the filtrate was concentrated under vacuum to give the crude product which was used as such without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312233B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-84e481538b424c1098fee51d75ef8136 |
| Source note | uspto-grants-2007_12 |