HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Nitroquinoline → 7-Aminoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Nitroquinoline | HCID 11946 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 7-Aminoquinoline | HCID 11377 | 95.9% |
Reaction Steps
A mixture of 7-nitroquinoline (0.30 g, 0.0017 mol; Specs, Inc.), 10% Pd—C (50 mg), and MeOH (20 mL) was stirred under H2 (1 atm) for 2 h. The mixture was filtered and the filtrate was concentrated to give a yellow solid (235 mg, 95%). LC-MS: 0.33 min, 145.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312233B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-dbd05ba4407b4126811b27d90fa44957 |
| Source note | uspto-grants-2007_12 |