HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 2-(Bromomethyl)-4,6-dimethylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | 2,4,6-Trimethylpyridine | HCID 7953 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 2-(Bromomethyl)-4,6-dimethylpyridine | HCID 22280405 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
A solution of 2,4,6-collidine (1 mmole) in carbon tetrachloride was treated with NBS (5 mmole) and dibenzoyl peroxide (0.25 mmole) at 80° C. for 12 h. The reaction mixture was cooled to 0° C. and the precipitate was filtered. The filtrate was concentrated under vacuum. Chromatography gave 2-bromomethyl-4,6-dimethylpyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312219B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-9f007e944bda44749aad3153c0e5f420 |
| Source note | uspto-grants-2007_12 |