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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 970703Generated: October 30, 2026

Selenium Dioxide → 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one

https://huagongshe.com/reaction/970703

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSelenium DioxideHCID 24007—
Reactant4,5-Dimethyl-1,3-dioxol-2-oneHCID 142210—
Solvent1,4-DioxaneHCID 31275—
Product4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-oneHCID 10510878—

Reaction Steps

A solution of 4,5-dimethyl-2-oxo-1,3-dioxolene (1 mmole) and selenium dioxide (2.5 mmole) in dioxane was heated at reflux for 1 h. Evaporation, extraction and chromatography gave 5-methyl-4-hydroxymethyl-2-oxo-1,3-dioxolene as a yellow oil. TLC: Rf=0.5, 5% MeOH-dichloromethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07312219B2
Source datasetuspto-grants-2007_12
ORD IDord-99ef50182bce4e41a6df2969ed5b36d7
Source noteuspto-grants-2007_12