HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)benzoic acid → [4-(Chloromethyl)phenyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)benzoic acid | HCID 74234 | — |
| Reactant | Borane;tetrahydrofuran | HCID 2723981 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | [4-(Chloromethyl)phenyl]methanol | HCID 5107660 | 79.8% |
Reaction Steps
4-Chloromethylbenzoic acid (20 mmol) was dissolved in 20 ml THF, then 30 ml borane/THF were added. The mixture was stirred for 16 hrs at room temperature, and then quenched with excess methanol. Evaporation yielded about 2.5 g 4-chloromethylbenzyl alcohol 36.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07312230B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-c1acdb545bcc468fa0a6ff4e7297a4b9 |
| Source note | uspto-grants-2007_12 |