Dimethyl 4-{3-[4-(3,3-dimethyl-2-oxobutoxy)-3-methylphenyl]propyl}phthalate → HCID 9800359, compound

HRID 970841Notes

Reaction equation

HRID 970841 reaction equation
[CH3:1][C:2]([CH3:32])([CH3:31])[C:3](=[O:30])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH2:13][CH2:14][C:15]2[CH:16]=[C:17]([C:25](OC)=[O:26])[C:18](=[CH:23][CH:24]=2)[C:19](OC)=[O:20])=[CH:8][C:7]=1[CH3:29].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[OH:26][CH2:25][C:17]1[CH:16]=[C:15]([CH2:14][CH2:13][CH2:12][C:9]2[CH:10]=[CH:11][C:6]([O:5][CH2:4][CH:3]([OH:30])[C:2]([CH3:31])([CH3:32])[CH3:1])=[C:7]([CH3:29])[CH:8]=2)[CH:24]=[CH:23][C:18]=1[CH2:19][OH:20]

Participants

3

Reactant 2

HCID 17983003Dimethyl 4-{3-[4-(3,3-dimethyl-2-oxobutoxy)-3-methylphenyl]propyl}phthalateHCID 21226445Aluminium lithium hydride

Product 1

HCID 9800359HCID 9800359, compound

Procedure

In a manner similar to Example 1h, by reacting 900 mg (2.1 mmol) of dimethyl 4-{3-[4-(3,3-dimethyl-2-oxobutoxy)-3-methylphenyl]propyl}phthalate with 375 mg (10 mmol) of lithium aluminum hydride. A thick colorless oil is obtained (m=780 mg, y=96%).

Workup

  1. customA thick colorless oil is obtained (m=780 mg, y=96%)

Sources & evidence

ORD record
ord-870bc6b7ad5542eea4aa65e4e83093b6
Source dataset
uspto-grants-2007_12
Patent number
US07312249B2

Reaction notes

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