Pyridine → [5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-phenylmethoxyoxolan-2-yl]methyl pyridine-3-carboxylate

HRID 97087Notes

Reaction equation

HRID 97087 reaction equation
[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[Cl:9].[CH2:10]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[O:17][CH:18]1[CH2:19][CH:20]([n:25]2[c:26](=[O:27])[nH:28][c:29](=[O:30])[c:31]([F:33])[cH:32]2)[O:21][CH:22]1[CH2:23][OH:24].[cH:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1>>[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[O:24][CH2:23][CH:22]1[CH:18]([O:17][CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:19][CH:20]([n:25]2[c:26](=[O:27])[nH:28][c:29](=[O:30])[c:31]([F:33])[cH:32]2)[O:21]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 82604Nicotinoyl chlorideHCID 136874745-Fluoro-1-[5-(hydroxymethyl)-4-phenylmethoxyoxolan-2-yl]pyrimidine-2,4-dione

Product 1

HCID 178525268[5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-phenylmethoxyoxolan-2-yl]methyl pyridine-3-carboxylate

Sources & evidence

ORD record
ord-d92c3dc2702d4b6a91eb8ef0d0482665
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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